CBD Endocannabinoid System- A Quick Guide

Posted on January 20th, 2022 to Information

The endocannabinoid system is a biological system composed of endocannabinoids, cannabinoid receptors, and modulating bodily enzymes. It’s referred to as a signal network or a regulatory system to maintain homeostasis in the body. Research shows that the endocannabinoid system (ECS) is present in all vertebrates: mammals, birds, reptiles, amphibians, and fish.

History of the Endocannabinoid system (ECS) :

Let’s start with some time travel. Prof. Allyn Howlett of Saint-Louis University in Missouri (USA) discovered in 1987 that the elements of the cannabis plant might alter human bodies. Moreover, she found a mechanism that allows those components to interact via specific receptors.

Not long after and till today, science has reopened its doors to the world of cannabis and hemp, and scientists are constantly uncovering new advantages. That is why ECS is a hot topic.

Functions of the endocannabinoid system – who is responsible?

ECS regulates various physiological processes, including appetite, hunger, satiety, pain- sensation and transmission, mood, memory, apoptosis, metabolism, inflammation, digestion, immunity, neuroprotection, and reproductive health.

Components of ECS:

1- Endocannabinoids:

Endocannabinoids are endogenous cannabinoids within the body. There are two primary ones, Anandamide (N-Arachidonoylethanolamide) and 2-AG (2- arachidonoylglycerol), which interact with the CB1, CB2, and CB3 receptors.

2- Cannabinoid Receptors:

CB1 receptors: These receptors are among the most abundant receptor types in the brain, spinal cord, and some organs such as the intestine. CB1 receptors are in charge of cognitive function, pain perception, and information processing. For example, they interact with THC to produce the feeling of high or a sense of euphoria. They also have power over your memory creation.

CB2 receptors: The CB2 receptor is located primarily in the gut immune system. These receptors link to pain transmission, inflammation, gut function, motility, energy balance, glucose and lipid metabolism, and reproductive health.

CB3 receptors: These receptors relate to reducing inflammation, healing tissue damage, and regulating your metabolism. However, there haven’t been a lot of representative study results on CB3 receptors.

3- Enzymes,

FAAH and MAGL enzymes are molecules that accelerate chemical reactions in the body, completing the homeostatic regulation within the endocannabinoid system. These enzymes ensure that our bodies use endocannabinoids as needed.

Out of balance – let CBD support you.

When your endocannabinoid system is out of balance, your entire body suffers. In addition, the style of life and day-to-day activities typically significantly affect whether or not the inner methods are balanced. That is why you should constantly strive for a healthy lifestyle.

Now that you’ve learned more about your vital endocannabinoid system in this Quick Guide to CBD Endocannabinoid, it’s time to see if CBD may help you.

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