CBD for Parkinson’s Disease?
Posted on May 1st, 2023 to Uncategorized
What is Parkinson’s Disease
Parkinson’s disease (PD) is a progressive neurodegenerative disorder that affects the central nervous system. It is characterized by tremors, rigidity, and postural instability, and eventually leads to a decline in motor function and cognitive abilities. It is estimated that over 10 million people worldwide are affected by this disease, and it is the second most common neurodegenerative disorder after Alzheimer’s disease.
Parkinson’s Disease begins when the nerve cells that produce the neurotransmitter dopamine start to die off. The lack of dopamine impairs mood and movement, which is why an early sign of Parkinson’s disease is tremors in the hand. There is currently no cure for Parkinson’s Disease, but treatments can offer symptomatic relief.
Why CBD for Parkinson’s Disease?
Researchers have been increasingly interested in the use of cannabidiol (CBD) as a potential treatment for Parkinson’s Disease. CBD is a non-psychoactive compound derived from the cannabis plant, and it has been shown to have various therapeutic effects, including anti-inflammatory, anti-anxiety, and neuroprotective properties, making it a promising treatment for PD.
Researchers have conducted several clinical trials to evaluate the efficacy of CBD in patients with PD. One of the earliest studies was a double-blind, placebo-controlled trial conducted in 2014. The study included 21 PD patients who researchers randomly assigned to receive either CBD or placebo for six weeks. The results showed that CBD significantly improved motor scores compared to placebo, with no significant adverse effects. Another study on non-medicated Parkinson’s patients reported improvements in quality of life and reduction in non-motor symptoms while taking CBD.
CBD protects against dopaminergic neuron damage through its anti-inflammatory and antioxidant properties. Inflammation and oxidative stress cause neurodegeneration in PD. CBD inhibits the production of pro-inflammatory cytokines and promotes the production of anti-inflammatory cytokines, reducing inflammation. CBD also has antioxidant properties, which means it can lessen damage to cells and tissues that PD causes.
A study published in the Journal of Psychopharmacology showed that CBD improved motor function and reduced the severity of tremors in Parkinson’s Disease. Another study published in the European Journal of Pain showed that CBD reduced motor symptoms and pain in mice with PD. CBD can also improve non-motor symptoms in Parkinson’s patients. It can reduce anxiety, depression, and sleep disturbances that can significantly reduce a patient’s quality of life. CBD has anxiolytic and antidepressant effects. CBD reduced anxiety in patients with social anxiety disorder. Another study showed that CBD reduced anxiety and cognitive impairment in patients with PD. CBD also has potential as a treatment for REM sleep behavior disorder (RBD), which is a common sleep disorder in PD patients. Patients can experience violent, physically active dreams that can cause injury to themselves or their bed partner. CBD improved sleep in patients with RBD.
CBD Side Effects:
Patients generally tolerate CBD well. However, some patients may experience side effects such as fatigue, drowsiness, and dry mouth. CBD can also interact with other medications, so it is essential to consult with a healthcare provider before starting treatment. Older patients may be more sensitive to the psychoactive effects of THC, and may prefer THC-free CBD products.
Interested in CBD for Parkinson’s Disease?
CBD shows promise as a treatment option for Parkinson’s disease. Its neuroprotective, anti-inflammatory, and antioxidant properties may help slow down the progression of the disease and improve motor function. CBD may also help alleviate non-motor symptoms such as anxiety, depression, and sleep disturbances, which can significantly impact a patient’s quality of life.
Exploring CBD for the first time can be overwhelming. Luckily you don’t have to do it alone. At Hempeutics Pharmacy, our board-certified pharmacist, Dr. Peggy, meets with patients one-on-one to guide them through the process. Dr. Peggy can recommend CBD products, or makes custom CBD products based on a patient’s condition and needs. Hempeutics pharmacy also offers THC-free CBD Tinctures which Dr. Peggy recommends for those over 65.